KPV
10mg
⚠️ Not for human consumption. Research purposes only.
Description
KPV (Lys-Pro-Val) is a C-terminal tripeptide fragment derived from alpha-melanocyte stimulating hormone (α-MSH). It has been studied in preclinical models for its effects on NF-κB inflammatory signaling inhibition, with particular focus on mucosal and epithelial tissue inflammation models.
Key Areas of Study
- NF-κB pathway modulation research
- inflammatory cytokine signaling studies
- mucosal inflammation modeling
- α-MSH fragment analysis
Mechanisms Being Evaluated
KPV has been shown to enter cells and directly inhibit NF-κB activation by interacting with the p65 subunit, reducing transcription of pro-inflammatory cytokines including TNF-α, IL-6, and IL-1β. Studies have demonstrated these effects in both intestinal epithelial and dermal tissue models.
Commonly Researched Uses
NF-κB signaling pathway research, inflammatory cytokine modulation studies, mucosal barrier function investigations, α-MSH-derived peptide analysis
Recent Studies and Trials
The following peer-reviewed studies and clinical trials have investigated the properties and applications of this peptide:
KPV Peptide Anti-Inflammatory Effects
Published: 2006
Melanocortin Peptides in Inflammation
Published: 2012
KPV in Inflammatory Bowel Disease
Published: 2013
Note: These studies are provided for informational and research purposes only. This product is not intended for human consumption.