CJC no DAC

10mg

⚠️ Not for human consumption. Research purposes only.

Description

CJC-1295 without DAC (Modified GRF 1-29) is a synthetic 29-amino acid analog of growth hormone-releasing hormone (GHRH) with amino acid substitutions at positions 2, 8, 15, and 27 to enhance metabolic stability. It has been studied for its effects on pulsatile growth hormone secretion and GHRH receptor pharmacology.

Key Areas of Study

GHRH receptor pharmacology research
pulsatile GH secretion studies
growth hormone axis modulation analysis
peptide stability enhancement modeling

Mechanisms Being Evaluated

Modified GRF 1-29 binds to the GHRH receptor on anterior pituitary somatotroph cells, stimulating endogenous growth hormone release in a pulsatile, physiological pattern. Its amino acid substitutions reduce enzymatic degradation, extending its half-life compared to native GHRH in preclinical studies.

Commonly Researched Uses

GHRH receptor binding research, pulsatile growth hormone secretion studies, peptide stability and pharmacokinetics investigations, somatotroph signaling analysis